In the year since the events of Arkham Asylum, former warden Quincy Sharp is now Mayor of Gotham City and authorizes the development of a new prison facility comprised of a large section of Gotham's slums. Known as Arkham City, it is run by the mysterious Professor Hugo Strange. Batman knows that something is not right. Allowing some of the city's most dangerous villains free rein within the open-air prison has disaster written all over it. Furthermore, there's something about Strange that Batman does not like.
Featuring a plot written by Paul Dini of Batman: The Animated Series fame. Kevin Conroy and Mark Hamill once more voice Batman and The Joker respectively. The cast also features Corey Burton as Hugo Strange, Tara Strong as Harley Quinn, Grey DeLisle as Catwoman, Nolan North as The Penguin, Maurice LaMarche as Mr. Freeze, Troy Baker as Two-Face, Wally Wingert as The Riddler, and many more.